Selected Publications
The fate of decisions
Development of multicellular organisms relies on the cells’ ability to become specialized to fulfill diverse functions. Changing cell identity may be harmful, as in cancerogenesis, but it is widely exploited in medicine for the generation of pluripotent cells and in plant biotechnology for re-juvenation and clonal propagation. Therefore, understanding the processes that maintain cell differentiation states is of great importance. Recent research has established that cell differentiation states differ in their epigenomes, and it is thought that epigenetic barriers serve to prevent cells from uncontrolled changes of identity. Here, we aim to decipher the epigenetic barriers that restrict spontaneous fate changes of plant cells and how they can break down during development or disease.
Image by: Alyona Minina
Image by: Panagiotis Moschou
Image by: Alyona Minina
Image by: Alyona Minina
